A rare smallpox relative has jumped from Africa to four other continents with a disproportionate number of cases in men who have sex with men.

With the COVID-19 pandemic still raging, a second public health threat has the world on high alert: a global outbreak of monkeypox. As of 26 May, two dozen countries in the Americas, Europe, North Africa, the Middle East, and Australia had reported more than 350 suspected and confirmed cases of the disease, a much milder cousin of smallpox, the deadly scourge that the World Health Organization (WHO) deemed eradicated in 1980.

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